Product Details

Akynzeo

Netupitant + Palonosetron Hydrochloride
300 mg + 0.5 mg
Capsule


DIN/PIN/NPN

02468735

Manufacturer

Knight Therapeutics Inc.

Formulary Listing Date

2019-06-28  

Unit Price

144.0075

Amount MOH Pays

144.0075

Coverage Status

Limited Use Product

ODB Formulary Therapeutic Classification

Therapeutic Note

NO

ATC Code

A04AA55

Interchangeable Products

NO  

LU Clinical Criteria

LU Code Auth. Period Clinical Criteria
561 1 year

In combination with dexamethasone for once per-cycle treatment in adult patients for:

- Prevention of acute and delayed nausea and vomiting associated with highly emetogenic cancer chemotherapy (HEC).

Highly emetogenic chemotherapy (HEC) regimens:

- Cisplatin-based chemotherapy where a single daily dose is greater than or equal to 70mg per meter squared

- Cisplatin and cyclophosphamide combinations where the single daily dose of cisplatin is greater than or equal to 50mg per meter squared

- Non-cisplatin based highly emetogenic chemotherapy (such as those containing anthracycline greater than or equal to 60mg per meter squared plus cyclophosphamide).

Dosage: Recommend Netupitant/Palonosetron 300mg/0.5mg orally on Day 1 approximately 1 hour prior to the start of each HEC.

562 1 year

In combination with dexamethasone for once per-cycle treatment in adult patients for:

- Prevention of acute nausea and vomiting associated with moderately emetogenic cancer therapy (MEC) that is uncontrolled by a 5-hydroxytryptamine-3 (5-HT3) receptor antagonist (RA) alone in a previous cycle.

Dosage: Recommend Netupitant/Palonosetron 300mg/0.5mg orally on Day 1 approximately 1 hour prior to the start of each MEC cycle.

 

EAP Criteria

NO

Product Monograph

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