Product Details
Apo-Ketoconazole
Ketoconazole200 mg
Tablet
DIN/PIN/NPN
02237235
Manufacturer
Apotex Inc.
Formulary Listing Date
1999-09-15
Unit Price
0.9393
Amount MOH Pays
0.9393
Coverage Status
General Benefit
ODB Formulary Therapeutic Classification
Therapeutic Note
Apo-Ketoconazole: A low pH is necessary for absorption. Antacids, anticholinergics/antispasmodics, H2-blockers, and omeprazole may decrease absorption. Ketoconazole is a potent inhibitor of hepatic oxidation of drugs and may cause significant elevation of blood levels of astemizole, cisapride, cyclosporine, terfenadine, theophylline and warfarin. Potentially fatal arrhythmias (torsade de pointes) can occur with the combination of ketoconazole and astemizole, cisapride or terfenadine. Insulin requirements may be reduced. Hepatotoxicity occurs in approximately 1 in 1500 patients treated with ketoconazole for onychomycosis; female gender, pre-existing disease, alcoholism and greater than 2 weeks of therapy are pre-disposing factors.
ATC Code
J02AB02
Interchangeable Products
DIN/ PIN/ NPN | Brand name | Unit Price | Amount MOH pays |
---|---|---|---|
02231061 | Teva-Ketoconazole | 0.9393 | 0.9393 |
00633836 | Nizoral | NA | NA |
02237235 | Apo-Ketoconazole | 0.9393 | 0.9393 |