Product Details

Apo-Ketoconazole

Ketoconazole
200 mg
Tablet


DIN/PIN/NPN

02237235

Manufacturer

Apotex Inc.

Formulary Listing Date

1999-09-15  

Unit Price

0.9393

Amount MOH Pays

0.9393

Coverage Status

General Benefit

ODB Formulary Therapeutic Classification

Therapeutic Note

Apo-Ketoconazole: A low pH is necessary for absorption. Antacids, anticholinergics/antispasmodics, H2-blockers, and omeprazole may decrease absorption. Ketoconazole is a potent inhibitor of hepatic oxidation of drugs and may cause significant elevation of blood levels of astemizole, cisapride, cyclosporine, terfenadine, theophylline and warfarin. Potentially fatal arrhythmias (torsade de pointes) can occur with the combination of ketoconazole and astemizole, cisapride or terfenadine. Insulin requirements may be reduced. Hepatotoxicity occurs in approximately 1 in 1500 patients treated with ketoconazole for onychomycosis; female gender, pre-existing disease, alcoholism and greater than 2 weeks of therapy are pre-disposing factors.

ATC Code

J02AB02

Interchangeable Products

DIN/ PIN/ NPN Brand name Unit Price Amount MOH pays
02231061 Teva-Ketoconazole 0.9393 0.9393
00633836 Nizoral NA NA
02237235 Apo-Ketoconazole 0.9393 0.9393
 

LU Clinical Criteria

NO  

EAP Criteria

NO

Product Monograph

View Monograph