Product Details
Teva-Ketoconazole
Ketoconazole200 mg
Tablet
DIN/PIN/NPN
02231061
Manufacturer
Teva Canada Limited
Formulary Listing Date
2000-01-17
Unit Price
0.9393
Amount MOH Pays
0.9393
Coverage Status
General Benefit
ODB Formulary Therapeutic Classification
Therapeutic Note
Teva-Ketoconazole: A low pH is necessary for absorption. Antacids, anticholinergics/antispasmodics, H2-blockers, and omeprazole may decrease absorption. Ketoconazole is a potent inhibitor of hepatic oxidation of drugs and may cause significant elevation of blood levels of astemizole, cisapride, cyclosporine, terfenadine, theophylline and warfarin. Potentially fatal arrhythmias (torsade de pointes) can occur with the combination of ketoconazole and astemizole, cisapride or terfenadine. Insulin requirements may be reduced. Hepatotoxicity occurs in approximately 1 in 1500 patients treated with ketoconazole for onychomycosis; female gender, pre-existing disease, alcoholism and greater than 2 weeks of therapy are pre-disposing factors.
ATC Code
J02AB02
Interchangeable Products
DIN/ PIN/ NPN | Brand name | Unit Price | Amount MOH pays |
---|---|---|---|
02231061 | Teva-Ketoconazole | 0.9393 | 0.9393 |
00633836 | Nizoral | NA | NA |
02237235 | Apo-Ketoconazole | 0.9393 | 0.9393 |