Product Details
Jamteki
Ustekinumab90 mg/mL
Solution for Subcutaneous Injection
1-mL Single-Use Prefilled Syringe (Preservative-Free)
DIN/PIN/NPN
02543044
Manufacturer
Jamp Pharma Corporation
Formulary Listing Date
2024-04-30
Unit Price
2755.8840
Amount MOH Pays
2755.8840
Coverage Status
Limited Use Product
ODB Formulary Therapeutic Classification
Therapeutic Note
NO
ATC Code
L04AC05
Interchangeable Products
NOLU Clinical Criteria
LU Code | Auth. Period | Clinical Criteria |
---|---|---|
668 | 1 year | For the treatment of *severe plaque psoriasis in patients who have experienced failure, intolerance, or have a contraindication to adequate trials of several standard therapies**. Claims for the first 6 months must be written by a dermatologist. Monitoring of patients is required to determine if continuation of therapy beyond 12 weeks is required. Patients not responding adequately at 12 weeks should have treatment discontinued. *Definition of severe plaque psoriasis:
**Definition of failure, intolerance or contraindication to adequate trials of standard therapies:
Maintenance/Renewal: After 3 months of therapy, patients who respond to therapy should have:
Recommended dose: The recommended dose of ustekinumab is 45mg administered subcutaneously at weeks 0 and 4, then every 12 weeks thereafter. Alternatively, 90mg may be used in patients with a body weight of over 100kg. In patients weighing over 100kg, both the 45mg and 90mg doses were shown to be efficacious. However, 90mg was efficacious in a higher percentage of these patients. For patients who inadequately respond to dosing every 12 weeks, consideration may be given to treating as often as every 8 weeks. If the patient has not responded after 12 weeks of treatment, the prescriber should consider switching to an alternative biologic agent. |
669 | 1 year | For the treatment of psoriatic arthritis in patients who have severe active disease (greater than or equal to 5 swollen joints and radiographic evidence of psoriatic arthritis) despite: i) treatment with methotrexate (20mg/week) for at least 3 months; AND ii) one of leflunomide (20mg/day) or sulfasalazine (1g twice daily) for at least 3 months. If the patient has documented contraindications or intolerances to methotrexate, then only one of leflunomide (20mg/day) or sulfasalazine (1g twice daily) for at least 3 months is required. Maintenance/Renewal: After 12 months of treatment, maintenance therapy is funded for patients with objective evidence of at least a 20 percent reduction in swollen joint count and a minimum of improvement in 2 swollen joints over the previous year. For funding beyond the second year, the patient must have objective evidence of preservation of treatment effect. Therapy must be prescribed by a rheumatologist or a physician with expertise in rheumatology. The recommended dosing regimen is 45mg administered subcutaneously at weeks 0 and 4, then every 12 weeks thereafter. Alternatively, 90mg may be used in patients with a body weight greater than 100kg. Ustekinumab may be used alone or in combination with methotrexate (MTX). |