Product Details
Tukysa
Tucatinib150 mg
Tablet
DIN/PIN/NPN
02499835
Manufacturer
Seagen Canada Inc.
Formulary Listing Date
2023-02-21
Unit Price
119.5000
Amount MOH Pays
119.5000
Coverage Status
Exceptional Access Program Product
ODB Formulary Therapeutic Classification
Therapeutic Note
NO
ATC Code
L01EH03
Interchangeable Products
NOLU Clinical Criteria
NOEAP Criteria
Therapeutic Class | Reimbursement Criteria |
---|---|
Oncology Drugs | Tucatinib
Initial criteria: For the treatment of adult patients with HER-2 positive locally advanced or metastatic breast cancer in patients meeting ALL the following criteria:
Exclusion criteria: Patients who have experienced disease progression on capecitabine used in a prior line of therapy. Notes:
Renewal Criteria: Recommended dose: Tucatinib is funded in combination with capecitabine and trastuzumab at the recommended doses as follows: Capecitabine 1000 mg/m2 orally twice daily on days 1 to 14 of every 21-day cycle. Trastuzumab 8 mg/kg as a loading dose intravenously (IV) on day 1 of the first cycle, followed by 6 mg/kg IV every 21 days until disease progression or unacceptable toxicity, whichever comes first. (Note: Other dosing options may be administered. Please refer to Ontario Health Cancer Care Ontario) Approval Duration (Initials): 6 months Approval Duration of first renewal: 6 months Approval Duration of renewals: 1 year EAP Drug Request Form: |